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US-Iran Talks in Islamabad: Key Details on Timing, Agenda, and Mediators

Published On Sat, 11 Apr 2026
Fatima Hasan
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It has been more than six weeks since the US–Iran conflict began, and both sides now appear ready to begin negotiations, with Pakistan hosting the talks. A fragile two-week ceasefire is currently holding, while Pakistan has stepped in as a mediator amid rising regional instability that has already led to significant loss of life, disruption of global energy supplies, and tensions over key shipping routes. Meanwhile, Israel’s continued strikes in Lebanon have added further complexity to the situation.
The talks are scheduled to take place this weekend in Islamabad, following an invitation from Pakistani Prime Minister Shehbaz Sharif, with discussions expected to begin on Saturday morning. The Iranian delegation reportedly arrived late Friday night, while the US delegation, led by Vice President JD Vance along with senior officials including Steve Witkoff and Jared Kushner, is en route. Although the exact venue has not been officially confirmed, reports suggest it could be held at the Serena Hotel in Islamabad.
The agenda is expected to focus on competing proposals exchanged between the two sides, including a 15-point US plan and a 10-point Iranian response. Washington is said to be pushing for limits on Iran’s enriched uranium stockpile and broader strategic concessions, while Tehran is seeking sanctions relief, influence over key maritime routes, and an end to regional military actions. The role of Lebanon remains uncertain, with Iran reportedly insisting that a ceasefire there is a precondition for meaningful talks, while Israel continues its operations in the region.
Pakistan’s role as mediator is rooted in its long-standing diplomatic ties with both countries. It maintains strong relations with Iran, including shared borders and historical links, while also being a Major Non-NATO Ally of the United States. Islamabad has reportedly coordinated closely with both sides in recent days, with additional diplomatic backing involving regional partners.
To facilitate the high-level meeting, Pakistan has implemented strict security measures in Islamabad, including a temporary public holiday, traffic restrictions, and increased deployment of security personnel. The talks are expected to be conducted indirectly, with both delegations seated separately while Pakistani officials act as intermediaries, similar to earlier mediation efforts.
Disclaimer: This image is taken from Hindustan Times.